产品货号：
Z13142
中文名称：
CHEK2抗体
英文名称：
Anti-CHEK2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CHEK2 Antibody |
| 指标别名 | CDS1;CHEK2;Chk2;HuCds1;LFS2;PP1425;RAD53 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | CHEK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Chk2 antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human Chk2.The immunogen is located within the first 50 amino acids of Chk2. |
| 计算分子量 | 61kDa |
| 成分 | Chk2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Chk2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The p53 tumor-suppressor gene integrates numerous signals that control cell life and death.Several novel molecules involved in p53 signaling,including Chk2,p53R2,p53AIP1,Noxa,PIDD,and PID/MTA2,were recently discovered.The checkpoint kinase Chk2 is the mammalian homologue of yeast Cds1/Rad53.In response to DNA damage,the checkpoint kinase ATM phosphorylates and activates Chk2,which in turn directly phosphorylates and activates p53.Chk2 serves as ATM downstream effector to mediate activation of p53.Chk2 also phosphorylates and activates BRCA1,the product of a tumor suppressor gene that is mutated in breast and ovarian cancer. |
| Uniprot ID | O96017 |
| 基因名全称 | CHK2 checkpoint homolog (S.pombe) |
| 蛋白名全称 | CHK2 checkpoint homolog (S.pombe) |
| 推荐稀释比 | Chk2 antibody can be used for detection of Chk2 by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 1μg/mL.For immunofluorescence start at 5μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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